Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151412 | 0.85 | CACNA1B (0.39) | PTPN1PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL6150912 | 0.85 | CACNA1B (0.39) | PTPN1PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL5358773 | 0.82 | LMNA (0.55) | PPARGPPARAFFAR1ALDH1A1PPARD | |
| SCHEMBL5364045 | 0.80 | EPOR (0.54) | PTPN1EPORPPARGPPARAFFAR1 | |
| SCHEMBL5357860 | 0.78 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5395073 | 0.77 | PPARG (0.43) | PTPN1PPARGPPARAALDH1A1PPARD | |
| SCHEMBL7150900 | 0.76 | SRR (0.56) | PTPN1PPARGPPARAALDH1A1PPARD | |
| SCHEMBL5383333 | 0.76 | MAPK1 (0.44) | PTPN1PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL14366607 | 0.76 | MAPK1 (0.44) | PTPN1PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL6150658 | 0.76 | PPARA (0.45) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |