SCHEMBL6151302

SCHEMBL6151302

Cc1csc(C)c1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5153665 0.77
SCHEMBL8563636 0.72
SCHEMBL3041681 0.72
Hydrochloric Acid SCHEMBL3033866 0.70
SCHEMBL12767136 0.69 CYP1A2 (0.31)
SCHEMBL765340 0.69
SCHEMBL24924406 0.69 POLB (0.31)
SCHEMBL10714638 0.69
SCHEMBL23046370 0.69 NOS1 (0.30)
SCHEMBL3792755 0.69 MAPT (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178336-B Method for synthesizing N-aryl ketimine by acid catalytic ketal method and application 西安近代化学研究所 2025-04-25 CN claimed
CN-116178336-A Method for synthesizing N-aryl ketimine by acid catalytic ketal method and application 西安近代化学研究所 2023-05-30 CN claimed
CN-110066268-B Preparation method of 3-amino-2, 4-dimethylthiophene 北京颖泰嘉和生物科技股份有限公司 2020-11-06 CN claimed
CN-110066268-A The preparation method of 3- amino -2,4- thioxene 北京颖泰嘉和生物科技股份有限公司 2019-07-30 CN claimed
CN-109422602-A A kind of method of asymmetric hydrogenation imines preparation Chiral Amine 中国科学院大连化学物理研究所 2019-03-05 CN claimed
CN-102898329-B Method for synthesizing N-aryl ketoimine by acidic catalytic dehydration XIAN MODERN CHEMISTRY RES INST 2014-12-10 CN claimed
CN-102951980-A Asymmetric catalytic hydrogenation method of imine SINOCHEM CORP 2013-03-06 CN claimed
CN-102898329-A Method for synthesizing N-aryl ketoimine by acidic catalytic dehydration XIAN MODERN CHEMISTRY RES INST 2013-01-30 CN claimed
CN-101781230-B Method for synthesizing imine by catalytic dehydration SINOCHEM CORP 2012-11-07 CN claimed
CN-101781230-A Method for synthesizing imine by catalytic dehydration SHENYANG RES INST CHEMICAL IND 2010-07-21 CN claimed
US-12624023-B2 Sulfonylurea derivatives and uses thereof NodThera Limited (GB) 2026-05-12 US disclosed
EP-3983407-B1 SULFONYLUREA DERIVATIVES AND USES THEREOF NODTHERA LTD (GB) 2025-11-12 EP disclosed
CN-116178336-B Method for synthesizing N-aryl ketimine by acid catalytic ketal method and application 西安近代化学研究所 2025-04-25 CN disclosed
US-20250101015-A1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-03-27 US disclosed
US-20250084076-A1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-03-13 US disclosed
US-4666502-A Herbicidal N-thienyl-chloroacetamides SANDOZ LTD. (CH) 1987-05-19 US disclosed
CN-85106474-A The method for making of nitrogen-thiophene chlor(o)acetamide SANDOZ LTD 1987-04-29 CN disclosed
US-4472425-A FUNGICIDES SANDOZ LTD. (CH) 1984-09-18 US disclosed
US-4263205-A FOR COLORING POLYMERS, LACQUERS CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
EP-0006154-A1 Monoazo pigments and their use in colouring high molecular-weight organic material CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed