⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960253 | 0.72 | — | — | |
| SCHEMBL5153665 | 0.72 | — | — | |
| SCHEMBL6151302 | 0.72 | — | — | |
| SCHEMBL3790184 | 0.69 | — | — | |
| SCHEMBL3041681 | 0.68 | — | — | |
| SCHEMBL3717041 | 0.67 | IKBKB (0.41) | — | |
| SCHEMBL535647 | 0.67 | L3MBTL1 (0.52) | — | |
| SCHEMBL14125042 | 0.67 | KDM4E (0.41) | — | |
| SCHEMBL15751449 | 0.67 | POLB (0.35) | — | |
| Hydrochloric Acid SCHEMBL3033866 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691972-B1 | FURO 3,2-b]PYRIDINES AND THIENO 3,2-b]PYRIDINES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC (CA) | 1998-07-01 | — | — | EP | disclosed |
| EP-0691972-A1 | FURO 3,2-b]PYRIDINES AND THIENO 3,2-b]PYRIDINES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022869-A1 | FURO[3,2-b]PYRIDINES AND THIENO[3,2-b]PYRIDINES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1994-10-13 | — | — | WO | disclosed |