Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109662 | 0.86 | ALDH1A1 (0.56) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| SCHEMBL30723003 | 0.86 | ALDH1A1 (0.56) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| SCHEMBL17693662 | 0.80 | MAPT (0.49) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| SCHEMBL14174530 | 0.79 | MAPT (0.46) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| Ethane SCHEMBL5417384 | 0.77 | HCAR3 (0.55) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| SCHEMBL109327 | 0.76 | MAPT (0.46) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| SCHEMBL6151869 | 0.76 | MAPT (0.39) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| Hc Blue No. 1 SCHEMBL2467623 | 0.76 | ALDH1A1 (0.73) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| Hc Blue No. 1 SCHEMBL29683680 | 0.76 | ALDH1A1 (0.73) | MAPTNPSR1HCAR3ALDH1A1HTT | |
| SCHEMBL12286368 | 0.75 | ALDH1A1 (0.52) | MAPTNPSR1HCAR3ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6468316-B1 | DIRECT DYES HAVING COLORFASTNESS AND SOLUBILITY, USED FOR HUMAN HAIR | L'OREAL S.A. (FR) | 2002-10-22 | — | — | US | disclosed |
| US-6464731-B1 | 1-(3-(4-AMINO-2-CHLORO-5-NITROPHENYLAMINO)PROPYL)-3-METHYL-3H -IMIDAZOL-1-IUM BROMIDE USED AS DIRECT HAIR DYES; SOLUBILITY AND PHOTOSTABILITY | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| US-6383230-B1 | COLORFASTNESS, PHOTOSTABILITY, WATERPROOFING, WEATHERPROOFING | L'OREAL (FR) | 2002-05-07 | — | — | US | disclosed |
| EP-1022271-A1 | Cationic monobenzenic dyes, their use for the oxydative dyeing of keratinic fibres ,dye compositions and dyeing processes | L'OREAL (FR) | 2000-07-26 | — | — | EP | disclosed |
| EP-1020176-A2 | Use of cationic bis-nitrobenzenes for dyeing of keratinic fibers, dyeing compositions and dyeing process | L'OREAL (FR) | 2000-07-19 | — | — | EP | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |