SCHEMBL6151594

SCHEMBL6151594

C#CCOc1c(Cl)cc(OCc2ccccc2/C(=C\OC)C(=O)O)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.40
TP53 P04637 1/20 0.40
ALDH1A1 P00352 2/20 0.39
NR4A2 P43354 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
MRGPRX4 Q96LA9 2/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ABL1 P00519 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RIN1 Q13671 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
SLC26A4 O43511 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151596 1.00 HTT (0.40) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL5076493 0.91 HIF1A (0.39) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL6151595 0.91 HTT (0.42) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL6157649 0.90 HTT (0.39) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL6157644 0.90 HTT (0.39) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL5075979 0.88 RAB9A (0.46) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL5075974 0.88 RAB9A (0.46) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL5079482 0.87 MRGPRX4 (0.44) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL5079484 0.87 MRGPRX4 (0.44) HTTTP53ALDH1A1NR4A2RAB9A
SCHEMBL6151249 0.87 HIF1A (0.44) HTTTP53ALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed