Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157644 | 1.00 | HTT (0.39) | HTTPOLBALOX15NR4A2RAB9A | |
| SCHEMBL5074554 | 0.91 | HIF1A (0.39) | HTTPOLBALOX15NR4A2RAB9A | |
| SCHEMBL6151594 | 0.90 | HTT (0.40) | HTTNR4A2RAB9ANPC1TP53 | |
| SCHEMBL6151596 | 0.90 | HTT (0.40) | HTTNR4A2RAB9ANPC1TP53 | |
| SCHEMBL5075974 | 0.88 | RAB9A (0.46) | HTTNR4A2RAB9ANPC1TP53 | |
| SCHEMBL5075979 | 0.88 | RAB9A (0.46) | HTTNR4A2RAB9ANPC1TP53 | |
| SCHEMBL5079482 | 0.87 | MRGPRX4 (0.44) | HTTNR4A2RAB9ANPC1TP53 | |
| SCHEMBL5079484 | 0.87 | MRGPRX4 (0.44) | HTTNR4A2RAB9ANPC1TP53 | |
| SCHEMBL6151249 | 0.87 | HIF1A (0.44) | HTTRAB9ANPC1TP53MRGPRX4 | |
| SCHEMBL6151245 | 0.87 | HIF1A (0.44) | HTTRAB9ANPC1TP53MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |