Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73424 | 0.95 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28957948 | 0.86 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27154327 | 0.85 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL133182 | 0.81 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL93435 | 0.81 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL340147 | 0.81 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28617940 | 0.80 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1792183 | 0.80 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL394435 | 0.80 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3505241 | 0.80 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1234830-B1 | Method of preparing an organosilicon compound containing a methacryloxy functional group | DOW CORNING TORAY SILICONE (JP) | 2005-01-19 | — | — | EP | disclosed |
| US-6448427-B1 | REACTING AN ALKALI-METAL SALT OF (METH)ACRYLIC ACID WITH A HALOGEN SUBSTITUTED ORGANOSILICON COMPOUND IN THE PRESENCE OF A TERTIARY AMINE DIAZABICYCLO DERIVATIVE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-1234830-A2 | Method of preparing an organosilicon compound containing a methacryloxy functional group | Dow Corning Toray Silicone Co., Ltd. (JP) | 2002-08-28 | — | — | EP | disclosed |
| US-20020115878-A1 | METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP | DOW TORAY CO., LTD. (JP) | 2002-08-22 | — | — | US | disclosed |