SCHEMBL73424

SCHEMBL73424

C=C(C)C(=O)OCCC[Si](OC(C)OC)(OC(C)OC)OC(C)OC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.40
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151602 0.95 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL133182 0.86 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL93435 0.85 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28617940 0.84 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1804635 0.84 ALDH1A1 (0.42) TSHRALDH1A1
SCHEMBL71407 0.83 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
Alcohol SCHEMBL29001782 0.82 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25812302 0.82 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1227557 0.82 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28957948 0.81 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 966 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240093058-A1 POLYSILAZANE HARD COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2024-03-21 US claimed
EP-4329933-A1 HYDROLYTICALLY STABLE ZWITTERIONIC CHROMATOGRAPHIC MATERIALS Waters Technologies Corporation (US) 2024-03-06 EP claimed
EP-4274866-A1 POLYSILAZANE HARD COATING COMPOSITIONS Merck Patent GmbH (DE) 2023-11-15 EP claimed
EP-4223409-A1 LITHIUM ION ADSORBENTS Conductive Energy Inc. (CA) 2023-08-09 EP claimed
US-20230241581-A1 LITHIUM ION ADSORBENTS CONDUCTIVE ENERGY INC. (CA) 2023-08-03 US claimed
US-20220362741-A1 HYDROLYTICALLY STABLE ZWITTERIONIC CHROMATOGRAPHIC MATERIALS WATERS TECHNOLOGIES CORPORATION (US) 2022-11-17 US claimed
WO-2022229904-A1 HYDROLYTICALLY STABLE ZWITTERIONIC CHROMATOGRAPHIC MATERIALS WATERS TECHNOLOGIES CORPORATION (US) 2022-11-03 WO claimed
WO-2022148757-A1 POLYSILAZANE HARD COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-14 WO claimed
US-11092574-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2021-08-17 US claimed
US-11071969-B1 Porous carbon-heteroatom-silicon inorganic/organic materials for chromatographic separations and process for the preparation thereof WATERS TECHNOLOGIES CORPORATION (US) 2021-07-27 US claimed
WO-2002053664-A2 ABSORBENT, LUBRICIOUS COATING AND ARTICLES COATED THEREWITH KIMBERLY-CLARK WORLDWIDE, INC. (US) 2002-07-11 WO claimed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
EP-0268243-B1 Packing material and process for its production TOSOH CORP (JP) 1997-08-13 EP claimed
EP-0613681-B1 Nail lacquer primary film forming resin DOW CORNING (US) 1997-08-06 EP claimed
US-5389726-A Nail lacquer primary film forming resin DOW CORNING CORPORATION (US) 1995-02-14 US claimed
EP-0613681-A1 Nail lacquer primary film forming resin DOW CORNING CORPORATION (US) 1994-09-07 EP claimed
US-5302379-A Nail lacquer primary film forming resin DOW CORNING CORPORATION (US) 1994-04-12 US claimed
EP-0327006-B1 LOW EMISSION EMULSION PAINTS, COATINGS AND LATEX-BASED PLASTERS, AND METHOD FOR THEIR MANUFACTURE HOECHST AKTIENGESELLSCHAFT (DE) 1993-01-20 EP claimed
US-5079286-A CASTING RESINS BASED ON ACRYLIC ACID ESTERS HUELS TROISDORF AG (DE) 1992-01-07 US claimed
EP-0268243-A2 Packing material and process for its production Tosoh Corporation (JP) 1988-05-25 EP claimed