SCHEMBL6151650

SCHEMBL6151650

O=C(Oc1ccccc1)Oc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.59
MAPT P10636 2/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 4/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 2/20 0.49
AKR1C3 P42330 1/20 0.48
ALDH1A1 P00352 4/20 0.48
LMNA P02545 1/20 0.48
TSHR P16473 2/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
BLM P54132 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3978408 0.93 ELANE (0.67) ELANEMAPTMAPK1HSD17B10HPGD
SCHEMBL360782 0.84 KDM4E (0.68) MAPTHSD17B10HPGDKDM4EALDH1A1
Benzophenone SCHEMBL16721021 0.83 ELANE (0.64) ELANEALDH1A1TDP1KMT2A
SCHEMBL981154 0.83 KDM4E (0.72) ELANEMAPTMAPK1HSD17B10HPGD
SCHEMBL4392121 0.82 HSD17B10 (0.62) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL15789771 0.82 HSD17B10 (0.45) ELANEMAPTHSD17B10HPGDKDM4E
SCHEMBL14244732 0.82 HSD17B10 (0.45) ELANEMAPTHSD17B10HPGDKDM4E
SCHEMBL1914108 0.82 SLC6A3 (0.54) ELANEMAPTHSD17B10HPGDKDM4E
SCHEMBL474967 0.82 ELANE (0.67) ELANEMAPTMAPK1HSD17B10HPGD
SCHEMBL29358894 0.82 ELANE (0.67) ELANEMAPTMAPK1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100349952-C Method for producing polycarbonate GEN ELECTRIC (US) 2007-11-21 CN disclosed
CN-1610715-A Process for the production of polycarbonate GEN ELECTRIC (US) 2005-04-27 CN disclosed
EP-1427770-B1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GEN ELECTRIC (US) 2005-01-19 EP disclosed
EP-1427770-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-06-16 EP disclosed
US-20030120025-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2003-06-26 US disclosed
WO-2003022905-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-03-20 WO disclosed
US-6525163-B1 Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels GENERAL ELECTRIC COMPANY 2003-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120025-A1 Process for the production of polycarbonate RNGTT, CAPG, RPL30 ELANE 1186/4885MAPT 3934/4885MAPK1 2887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.