Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25488522 | 0.78 | HTR2C (0.40) | ACHEKMT2AMEN1NPC1HPN | |
| SCHEMBL7141443 | 0.76 | HDAC4 (0.37) | ACHEKMT2AMEN1NPC1HPN | |
| SCHEMBL1515269 | 0.73 | HTR2C (0.74) | ACHEKMT2AMEN1NPC1HPN | |
| SCHEMBL30717247 | 0.71 | ACHE (0.48) | ACHEKMT2AMEN1NPC1HPN | |
| SCHEMBL5852622 | 0.71 | ACHE (0.48) | ACHEKMT2AMEN1NPC1HPN | |
| M-Xylene SCHEMBL28189 | 0.71 | — | — | |
| M-Xylene SCHEMBL891494 | 0.71 | ACHE (1.00) | ACHENPC1ALDH1A1MAPK1LMNA | |
| M-Xylene SCHEMBL6397624 | 0.71 | — | — | |
| SCHEMBL7779276 | 0.70 | TSHR (0.54) | ACHEKMT2AMEN1NPC1HPN | |
| SCHEMBL14290386 | 0.70 | HTR2C (0.53) | ACHEKMT2AMEN1NPC1HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530389-B | Preparation method of 2-aryl cyclopropylamine compound | 东北师范大学 | 2020-06-09 | — | — | CN | claimed |
| CN-107522635-B | N-cyclopropyl nitrone derivatives and preparation method thereof | 东北师范大学 | 2020-02-14 | — | — | CN | claimed |
| CN-108530389-B | Preparation method of 2-aryl cyclopropylamine compound | 东北师范大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-107488090-B | Efficient catalytic asymmetric preparation method of N-cyclopropyl nitrone compound | 东北师范大学 | 2020-06-02 | — | — | CN | disclosed |
| CN-107522635-B | N-cyclopropyl nitrone derivatives and preparation method thereof | 东北师范大学 | 2020-02-14 | — | — | CN | disclosed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |