Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364117 | 0.89 | F10 (0.68) | F10ATMSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL5734564 | 0.84 | F10 (0.54) | F10ATMF2SMN1; SMN2GAA | |
| SCHEMBL6930063 | 0.84 | F10 (0.66) | F10 | |
| SCHEMBL5193868 | 0.84 | ATM (0.71) | F10ATMF2SMN1; SMN2GAA | |
| SCHEMBL7430344 | 0.84 | F10 (0.44) | F10 | |
| Hydrochloric Acid SCHEMBL6195419 | 0.83 | ATM (0.69) | F10ATMF2SMN1; SMN2GAA | |
| SCHEMBL5735457 | 0.82 | F10 (0.58) | F10ATMF2 | |
| SCHEMBL6195355 | 0.82 | ATM (0.61) | F10ATMSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL6198123 | 0.81 | ATM (0.60) | F10ATMSMN1; SMN2GAA | |
| SCHEMBL6734091 | 0.81 | F10 (0.57) | F10ATMF2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082303-B1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 2005-01-26 | — | — | EP | disclosed |
| US-6395731-B1 | ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2002-05-28 | — | — | US | disclosed |
| EP-1082303-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999057099-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 1999-11-11 | — | — | WO | disclosed |