Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306860 | 0.85 | LSS (0.50) | F10KLK1FASNHRH4MEN1 | |
| SCHEMBL6151772 | 0.84 | F10 (0.57) | F10 | |
| SCHEMBL6930063 | 0.81 | F10 (0.66) | F10KLK1 | |
| SCHEMBL6736928 | 0.80 | HRH4 (0.45) | F10KLK1FASNHRH4MEN1 | |
| SCHEMBL6725737 | 0.78 | LSS (0.50) | F10KLK1FASNMEN1KMT2A | |
| SCHEMBL6422301 | 0.78 | LSS (0.54) | F10HRH4MEN1KMT2AL3MBTL1 | |
| SCHEMBL6730941 | 0.73 | MEN1 (0.43) | F10KLK1FASNMEN1KMT2A | |
| SCHEMBL7364117 | 0.73 | F10 (0.68) | F10 | |
| SCHEMBL5735802 | 0.71 | CNR1 (0.44) | F10HRH4KMT2AL3MBTL1NPC1 | |
| SCHEMBL6298889 | 0.70 | USP2 (0.56) | HRH4MEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082321-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999057113-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 1999-11-11 | — | — | WO | disclosed |