Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.55 |
| ▸ | PPARG | P37231 | 10/20 | 0.55 |
| ▸ | PPARD | Q03181 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151784 | 1.00 | PPARA (0.55) | PPARAPPARGPPARDRAB9ANPC1 | |
| SCHEMBL5369659 | 0.81 | RAB9A (0.49) | PPARAPPARGPPARDRAB9ATSHR | |
| SCHEMBL5369666 | 0.81 | RAB9A (0.49) | PPARAPPARGPPARDRAB9ATSHR | |
| SCHEMBL6685635 | 0.81 | RAB9A (0.49) | PPARAPPARGPPARDRAB9ATSHR | |
| SCHEMBL6150506 | 0.80 | PPARA (0.57) | PPARAPPARGPPARDLMNATSHR | |
| SCHEMBL6149533 | 0.78 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL6150272 | 0.77 | PPARA (0.71) | PPARAPPARGPPARD | |
| SCHEMBL6152282 | 0.77 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6152283 | 0.77 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL27674855 | 0.77 | PPARA (0.81) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |