Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152988 | 0.92 | MAPT (0.49) | MAPTALDH1A1CYP3A4BCL6BCOR | |
| SCHEMBL6151373 | 0.84 | MAPT (0.50) | MAPTALDH1A1CYP3A4KAT2BLMNA | |
| SCHEMBL2471755 | 0.84 | MAPT (0.50) | MAPTALDH1A1CYP3A4KAT2BLMNA | |
| SCHEMBL23909 | 0.83 | MAPT (0.51) | MAPTALDH1A1CYP3A4BCL6BCOR | |
| Hydrochloric Acid SCHEMBL10713406 | 0.83 | MAPT (0.49) | MAPTALDH1A1CYP3A4KAT2BTDP1 | |
| SCHEMBL29378395 | 0.83 | MAPT (0.51) | MAPTALDH1A1CYP3A4BCL6BCOR | |
| SCHEMBL8355249 | 0.80 | MAPT (0.47) | MAPTALDH1A1CYP3A4KAT2BLMNA | |
| SCHEMBL10614428 | 0.77 | MAPT (0.52) | MAPTALDH1A1CYP3A4BCL6BCOR | |
| SCHEMBL2834179 | 0.76 | MAPT (0.46) | MAPTALDH1A1CYP3A4KAT2BBCL6 | |
| SCHEMBL27758391 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1CYP3A4KAT2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6464731-B1 | 1-(3-(4-AMINO-2-CHLORO-5-NITROPHENYLAMINO)PROPYL)-3-METHYL-3H -IMIDAZOL-1-IUM BROMIDE USED AS DIRECT HAIR DYES; SOLUBILITY AND PHOTOSTABILITY | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |