Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498147 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1NPSR1HDAC1LMNA | |
| SCHEMBL10610115 | 0.85 | MAPT (0.50) | MAPTALDH1A1NPSR1HDAC1LMNA | |
| SCHEMBL8350044 | 0.84 | MAPT (0.46) | MAPTALDH1A1NPSR1HDAC1LMNA | |
| SCHEMBL6152988 | 0.82 | MAPT (0.49) | MAPTALDH1A1NPSR1LMNACYP3A4 | |
| SCHEMBL8349257 | 0.81 | MAPT (0.44) | MAPTALDH1A1NPSR1HDAC1LMNA | |
| SCHEMBL6151373 | 0.81 | MAPT (0.50) | MAPTALDH1A1NPSR1LMNACYP3A4 | |
| SCHEMBL2471755 | 0.81 | MAPT (0.50) | MAPTALDH1A1LMNACYP3A4MEN1 | |
| SCHEMBL6151803 | 0.80 | MAPT (0.47) | MAPTALDH1A1LMNACYP3A4MEN1 | |
| SCHEMBL23909 | 0.80 | MAPT (0.51) | MAPTALDH1A1LMNACYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL10713406 | 0.80 | MAPT (0.49) | MAPTALDH1A1CYP3A4KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874618-A | REACTING 2-NITRO-PARAPHENYLENEDIAMINES SUBSTITUTED AT 5-POSITION BY HALOGEN ATOM WITH MERCAPTAN DERIVATIVE OR SALT IN A SOLVENT, FURTHER OXIDIZING FOR SULFUR; USEFUL AS HAIR DYE; REDUCED ALLERGIES; WASHING STABILITY | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |
| US-5735910-A | DIRECT HAIR DYES; WASHFASTNESS, COLORFASTNESS | L'OREAL (FR) | 1998-04-07 | — | — | US | disclosed |
| US-4419101-A | Chlorine-substituted nitro-para-phenylenediamines, a process for their preparation and their use in dyeing keratin fibres | L'OREAL (FR) | 1983-12-06 | — | — | US | disclosed |