Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566520 | 0.84 | POLB (0.54) | SMN1; SMN2KMT2AMEN1HPGDPOLB | |
| SCHEMBL1535140 | 0.81 | MAPT (0.52) | SMN1; SMN2KMT2AMEN1POLBPKM | |
| SCHEMBL366886 | 0.72 | MAPT (0.52) | SMN1; SMN2KMT2AMEN1POLBPKM | |
| SCHEMBL5827633 | 0.71 | MAPT (0.67) | SMN1; SMN2KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL7761933 | 0.67 | ALDH1A1 (0.58) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3729240 | 0.67 | TSHR (0.55) | KMT2AMEN1HPGDNPSR1FAAH | |
| SCHEMBL1857955 | 0.67 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28114496 | 0.67 | ALDH1A1 (0.58) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1371167 | 0.67 | ALDH1A1 (0.51) | SMN1; SMN2KMT2AMEN1POLBPKM | |
| SCHEMBL13685419 | 0.67 | MAPT (0.49) | SMN1; SMN2KMT2AMEN1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725826-B1 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RES CAMPAIGN TECH (GB) | 2005-01-26 | — | — | EP | disclosed |
| EP-0725826-A1 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-08-14 | — | — | EP | disclosed |
| WO-1996014420-A1 | INDUCIBLE CELL ABLATION | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-05-17 | — | — | WO | disclosed |
| WO-1995012678-A2 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-05-11 | — | — | WO | disclosed |