Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535140 | 0.88 | MAPT (0.52) | POLBPKMALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6151856 | 0.84 | NPC1 (0.46) | POLBPKMALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL366886 | 0.78 | MAPT (0.52) | POLBPKMALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1371167 | 0.78 | ALDH1A1 (0.51) | POLBPKMALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL304470 | 0.77 | CASP6 (0.55) | POLBALDH1A1DTYMKMEN1KMT2A | |
| SCHEMBL2728751 | 0.76 | TDP1 (0.50) | ALDH1A1DTYMKCYP1A2CYP2C19MEN1 | |
| SCHEMBL30527915 | 0.76 | TDP1 (0.50) | ALDH1A1DTYMKCYP1A2CYP2C19MEN1 | |
| SCHEMBL27501298 | 0.75 | CASP6 (0.53) | POLBALDH1A1DTYMKMEN1KMT2A | |
| SCHEMBL30252887 | 0.74 | TDP1 (0.54) | PKMALDH1A1DTYMKCYP1A2CYP2C19 | |
| SCHEMBL29163865 | 0.74 | TDP1 (0.51) | POLBPKMALDH1A1DTYMKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000938-A1 | Macromolecular covalent conjugates, methods for preparing and pharmaceutical compositions containing them | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1979-03-07 | — | — | EP | disclosed |