Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114962 | 0.84 | KDM4E (0.67) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3155583 | 0.84 | KDM4E (0.67) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14334463 | 0.81 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14163777 | 0.81 | KDM4E (0.69) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14331795 | 0.80 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7813547 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5930196 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14334376 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8846447 | 0.77 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL28434898 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511750-A1 | PROCESS FOR THE PREPARATION OF FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-03-09 | — | — | EP | claimed |
| US-20040266795-A1 | Process for the preparation of famciclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-12-30 | — | — | US | claimed |
| WO-2004099208-A1 | PROCESS FOR THE PREPARATION OF FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-11-18 | — | — | WO | claimed |
| CN-1812990-A | Process for the preparation of famciclovir | TEVA PHARMA (IL) | 2006-08-02 | — | — | CN | disclosed |
| US-20050143400-A1 | Process for preparing famciclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-06-30 | — | — | US | disclosed |
| EP-1511750-A1 | PROCESS FOR THE PREPARATION OF FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-03-09 | — | — | EP | disclosed |
| EP-1511750-A1 | PROCESS FOR THE PREPARATION OF FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-03-09 | — | — | EP | disclosed |
| US-20040266795-A1 | Process for the preparation of famciclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-12-30 | — | — | US | disclosed |
| US-20040266795-A1 | Process for the preparation of famciclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-12-30 | — | — | US | disclosed |
| WO-2004099208-A1 | PROCESS FOR THE PREPARATION OF FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004099208-A1 | PROCESS FOR THE PREPARATION OF FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266795-A1 | Process for the preparation of famciclovir | ADH1C, CPS1, PAICS | KDM4E 114/4885ALDH1A1 186/4885HPGD 3258/4885 |
| US-20050143400-A1 | Process for preparing famciclovir | MTAP, TPMT, RFC1 | KDM4E 604/4885ALDH1A1 1666/4885HPGD 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.