Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152122 | 1.00 | PPARD (0.41) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580642 | 0.89 | PTGER2 (0.41) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580639 | 0.89 | PTGER2 (0.41) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580638 | 0.87 | PTGES (0.44) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580635 | 0.87 | PTGES (0.44) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580731 | 0.86 | PSEN1 (0.47) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580734 | 0.86 | PSEN1 (0.47) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580428 | 0.85 | RXRA (0.46) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580432 | 0.85 | RXRA (0.46) | PPARDPPARGPTGESALOX5PSEN1 | |
| SCHEMBL5580472 | 0.83 | PTGES (0.41) | PPARDPPARGPTGESALOX5PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1604971-A1 | CINNAMYL ALCOHOL DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-14 | — | — | EP | disclosed |