Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25667874 | 0.82 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL24373241 | 0.78 | CYP1A2 (0.35) | CYP1A2 | |
| SCHEMBL29479121 | 0.78 | CYP1A2 (0.35) | CYP1A2 | |
| SCHEMBL22349118 | 0.77 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL25669467 | 0.77 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL31341820 | 0.75 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL18368384 | 0.75 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL23588974 | 0.71 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL10381160 | 0.68 | HTR1A (0.38) | CYP1A2 | |
| SCHEMBL25976800 | 0.68 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487796-A4 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORP (US) | 2005-11-16 | — | — | EP | disclosed |
| EP-1487796-A1 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003082826-A1 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |