Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.67 |
| ▸ | FAAH | O00519 | 4/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.67 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19835594 | 0.87 | TRPV1 (0.64) | EPHX2FAAHMCHR1MMP13TRPV1 | |
| SCHEMBL20805896 | 0.85 | EPHX2 (0.70) | EPHX2FAAHMCHR1TRPV1NAMPT | |
| SCHEMBL20805895 | 0.84 | EPHX2 (0.67) | EPHX2FAAHMCHR1TRPV1NAMPT | |
| SCHEMBL20805899 | 0.82 | MAPK14 (0.70) | EPHX2FAAHMCHR1MMP13NAMPT | |
| SCHEMBL20805897 | 0.82 | EPHX2 (0.73) | EPHX2FAAHMCHR1MMP13TRPV1 | |
| SCHEMBL6152168 | 0.81 | EPHX2 (0.68) | EPHX2FAAHMCHR1NAMPTRAF1 | |
| SCHEMBL4258215 | 0.80 | EPHX2 (1.00) | EPHX2FAAHTRPV1HDAC3HDAC4 | |
| SCHEMBL19358927 | 0.80 | EPHX2 (1.00) | EPHX2FAAHRAF1 | |
| SCHEMBL19358926 | 0.80 | EPHX2 (1.00) | EPHX2FAAHRAF1 | |
| SCHEMBL6107273 | 0.80 | MCHR1 (1.00) | EPHX2MCHR1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858338-B2 | Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190077785-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10858338-B2 | Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH) | FAAH, FAAH2, EPHX2 | EPHX2 3/4885FAAH 1/4885MCHR1 4118/4885 |
| US-20190077785-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | FAAH, FAAH2, EPHX2 | EPHX2 3/4885FAAH 1/4885MCHR1 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.