Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282846 | 1.00 | ADRB2 (0.42) | ADRB2ADRB3ADRB1DRD2DRD1 | |
| SCHEMBL5282855 | 1.00 | ADRB2 (0.42) | ADRB2ADRB3ADRB1DRD2DRD1 | |
| SCHEMBL5280173 | 0.92 | ADRB2 (0.48) | ADRB2ADRB3ADRB1DRD2DRD1 | |
| SCHEMBL5280167 | 0.92 | ADRB2 (0.48) | ADRB2ADRB3ADRB1DRD2DRD1 | |
| SCHEMBL5393168 | 0.90 | ADRB2 (0.47) | ADRB2ADRB3ADRB1DRD2DRD1 | |
| SCHEMBL5288433 | 0.88 | ADRB3 (0.45) | ADRB2ADRB3ADRB1 | |
| SCHEMBL5288452 | 0.88 | ADRB3 (0.45) | ADRB2ADRB3ADRB1 | |
| SCHEMBL6152016 | 0.87 | ADRB2 (0.41) | ADRB2ADRB3ADRB1 | |
| SCHEMBL5280870 | 0.87 | ADRB2 (0.41) | ADRB2ADRB3ADRB1 | |
| SCHEMBL5296071 | 0.87 | ADRB3 (0.41) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | disclosed |