Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354757 | 0.88 | FABP4 (0.57) | MAPTSMN1; SMN2THRBTP53NPC1 | |
| SCHEMBL13036112 | 0.76 | KMT2A (0.52) | MAPTSMN1; SMN2THRBTP53NPC1 | |
| SCHEMBL2779648 | 0.76 | HDAC1 (0.59) | MAPTSMN1; SMN2THRBTP53FNTA | |
| SCHEMBL353757 | 0.75 | NPC1 (0.49) | MAPTSMN1; SMN2THRBTP53NPC1 | |
| SCHEMBL2775334 | 0.75 | HDAC1 (0.48) | MAPTSMN1; SMN2THRBTP53FNTA | |
| SCHEMBL355352 | 0.73 | FABP4 (0.82) | MAPTSMN1; SMN2TP53HDAC1HDAC6 | |
| SCHEMBL14160797 | 0.71 | NPC1 (0.68) | MAPTSMN1; SMN2THRBTP53NPC1 | |
| SCHEMBL354539 | 0.70 | FABP4 (0.64) | MAPTSMN1; SMN2THRBTP53HDAC1 | |
| SCHEMBL354562 | 0.70 | FABP4 (0.64) | MAPTSMN1; SMN2TP53HDAC1HDAC6 | |
| SCHEMBL353478 | 0.70 | FABP4 (0.64) | MAPTSMN1; SMN2HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497453-A1 | METHODS FOR MEASURING PROTEIN KINASE AND PHOSPHATASE ACTIVITY | Amersham Biosciences UK Limited (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003089665-A1 | METHODS FOR MEASURING PROTEIN KINASE AND PHOSPHATASE ACTIVITY | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2003-10-30 | — | — | WO | disclosed |