SCHEMBL6152590

SCHEMBL6152590

CCCCC(=O)Oc1ccccc1S(=O)(=O)O

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.60
MEN1 O00255 1/20 0.60
RECQL P46063 1/20 0.60
KMT2A Q03164 1/20 0.60
POLM Q9NP87 2/20 0.45
POLK Q9UBT6 2/20 0.45
POLL Q9UGP5 2/20 0.45
POLH Q9Y253 2/20 0.45
ALOX15 P16050 1/20 0.42
PPARG P37231 1/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
PTGS2 P35354 1/20 0.39
POLB P06746 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ACLY P53396 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030621 0.95 KDM4E (0.55) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL29726411 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL29393577 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL29507312 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL5706066 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL38245 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL38840 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL10815664 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL38418 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL4220035 0.94 KMT2A (0.54) KDM4EMEN1RECQLKMT2APOLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6251612-B1 HYBRIDOMA; CHEAP AND SENSITIVE MONITORING OF WATER POLLUTION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-06-26 US claimed
EP-0834557-B1 Monoclonal antibodies to detergents and their degradation products, and their use in immunoassays JAPAN ENVIRO CHEMICALS LTD (JP) 2005-06-29 EP disclosed
US-6903217-B2 Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them AVENTIS PHARMA S.A. (FR) 2005-06-07 US disclosed
US-6603005-B2 Bactericides AVENTIS PHARMA S.A. (FR) 2003-08-05 US disclosed
US-20020111492-A1 Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them NOVEXEL (FR) 2002-08-15 US disclosed
US-6251612-B1 HYBRIDOMA; CHEAP AND SENSITIVE MONITORING OF WATER POLLUTION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-06-26 US disclosed
EP-0834557-A1 Monoclonal antibodies to detergents and their degradation products, and their use in immunoassays TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020111492-A1 Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them SYNJ1, NCAPD2, SYNJ2 KDM4E 4252/4885MEN1 250/4885RECQL 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.