Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 5/20 | 0.67 |
| ▸ | MMP13 | P45452 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141803 | 0.88 | ABL1 (0.57) | MMP12MMP13ABL1SCN10AEPHX2 | |
| SCHEMBL6451590 | 0.88 | ABL1 (0.57) | MMP12MMP13ABL1SCN10AMAPT | |
| SCHEMBL6463245 | 0.87 | MMP12 (0.56) | MMP12MMP13ABL1SCN10AEPHX2 | |
| SCHEMBL6450855 | 0.85 | MMP12 (0.55) | MMP12MMP13ABL1SCN10AEPHX2 | |
| SCHEMBL6450834 | 0.85 | ABL1 (0.54) | MMP12MMP13ABL1SCN10AEPHX2 | |
| SCHEMBL6141802 | 0.84 | MMP12 (0.60) | MMP12MMP13ABL1HDAC6SCN10A | |
| SCHEMBL6462719 | 0.82 | MMP12 (0.64) | MMP12MMP13ABL1HDAC6EPHX2 | |
| SCHEMBL6468492 | 0.82 | MMP12 (0.63) | MMP12MMP13ABL1HDAC6SCN10A | |
| SCHEMBL6374857 | 0.82 | MMP12 (0.61) | MMP12MMP13ABL1HDAC6IGF2BP2 | |
| SCHEMBL6511171 | 0.81 | MMP12 (0.62) | MMP12MMP13ABL1HDAC6SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493739-A1 | Thiophene derivatives of aminoacids, process for the preparation thereof and compositions containing them | Warner-Lambert Company LLC (US) | 2005-01-05 | — | — | EP | disclosed |