SCHEMBL6152784

SCHEMBL6152784

CCC/C(C)=N/NC(=O)c1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
ALDH1A1 P00352 3/20 0.59
MAPT P10636 3/20 0.59
GAA P10253 2/20 0.59
MEN1 O00255 2/20 0.59
NSD2 O96028 1/20 0.59
POLB P06746 1/20 0.59
GFER P55789 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.57
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
OGG1 O15527 2/20 0.55
HDAC3 O15379 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC2 Q92769 2/20 0.55
KDM4E B2RXH2 4/20 0.52
HPGD P15428 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6055295 1.00 KMT2A (0.59) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL6055291 1.00 KMT2A (0.59) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL1563268 0.89 MAPT (0.61) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL29586571 0.89 MAPT (0.61) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL1563270 0.89 MAPT (0.61) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL6634931 0.89 MAPT (0.61) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL6636836 0.84 OGG1 (0.70) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL1563372 0.82 MAPT (0.58) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL6635696 0.82 MAPT (0.58) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL1563371 0.82 MAPT (0.58) KMT2AALDH1A1MAPTGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095972-B1 Rubber composition and tire BRIDGESTONE CORP (JP) 2005-01-26 EP disclosed
US-6787595-B1 WEAR RESISTANCE; LOW HEAT BUILDUP; INCORPORATES CARBON BLACK OF SPECIFIC PROPERTIES BRIDGESTONE CORPORATION (JP) 2004-09-07 US disclosed
EP-1095972-A1 Rubber composition and tire Bridgestone Corporation (JP) 2001-05-02 EP disclosed