Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614957 | 0.84 | BCHE (0.47) | BCHETSHRMAPK1SIGMAR1ALDH1A1 | |
| SCHEMBL11682289 | 0.82 | BCHE (0.49) | BCHETSHRMAPK1SIGMAR1ALDH1A1 | |
| SCHEMBL9635933 | 0.81 | BCHE (0.45) | BCHETSHRMAPK1SIGMAR1ALDH1A1 | |
| SCHEMBL12124877 | 0.80 | TSHR (0.50) | BCHETSHRSIGMAR1ALDH1A1ADRA2B | |
| SCHEMBL5902506 | 0.80 | BCHE (0.44) | BCHETSHRSIGMAR1ALDH1A1ADRA2B | |
| SCHEMBL19479501 | 0.79 | BCHE (0.52) | BCHETSHRMAPK1SIGMAR1ALDH1A1 | |
| SCHEMBL11690049 | 0.77 | TSHR (0.47) | BCHETSHRSIGMAR1ALDH1A1ADRA2B | |
| SCHEMBL1302289 | 0.77 | TSHR (0.52) | BCHETSHRSIGMAR1ALDH1A1ADRA2B | |
| SCHEMBL615515 | 0.77 | ADRA2B (0.58) | TSHRSIGMAR1ALDH1A1ADRA2BHTR2A | |
| SCHEMBL12126080 | 0.77 | BCHE (0.54) | BCHETSHRSIGMAR1ALDH1A1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466287-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8067595-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090023927-A1 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1900740-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | Kabushiki Kaisha Yakult Honsha (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | TKT, DCK, COASY | BCHE 167/4885TSHR 3783/4885MAPK1 3286/4885 |
| US-20090023927-A1 | Process for producing tricyclic ketone | TKT, DCK, COASY | BCHE 167/4885TSHR 3783/4885MAPK1 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.