Methacrylic Acid

Methacrylic Acid

SCHEMBL6153040

C=C(C)C(=O)O.CC(=O)CC(N)=O

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
KDM4E B2RXH2 1/20 0.36
KDM6B O15054 1/20 0.36
KDM5C P41229 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
LMNA P02545 2/20 0.33
TGFBR1 P36897 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HTT P42858 1/20 0.32
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL1399515 0.84 TDP1 (0.50) TDP1KDM4EALDH1A1LMNATGFBR1
Methacrylic Acid SCHEMBL26187735 0.84 KDM4E (0.42) TDP1KDM4EKDM6BKDM5CEGLN1
Ethylene SCHEMBL4453305 0.84 LMNA (0.41) TDP1KDM4EKDM6BKDM5CEGLN1
Formaldehyde SCHEMBL8629053 0.84
SCHEMBL52890 0.84
SCHEMBL21332235 0.84 LMNA (0.47) TDP1KDM4EKDM6BKDM5CEGLN1
Acetone SCHEMBL11803293 0.81 MGAM (0.39) TDP1KDM4EKDM6BKDM5CEGLN1
Carbamic Acid SCHEMBL8703783 0.81 ACHE (0.41) TDP1KDM4EKDM6BKDM5CEGLN1
Benzene SCHEMBL7894713 0.81 KDM4E (0.40) TDP1KDM4EKDM6BKDM5CEGLN1
Methacrylic Acid SCHEMBL5428114 0.81 TDP1 (0.48) TDP1ALDH1A1LMNATGFBR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986611-B1 CROSS-LINKABLE SURFACE COATINGS AND PROCESS OF PREPARATION JOHNSON POLYMER LLC (US) 2005-01-26 EP disclosed
US-6090882-A Crosslinkable surface coatings and process of preparation S. C. JOHNSON COMMERCIAL MARKETS, INC. (US) 2000-07-18 US disclosed
EP-0873303-B1 ETHYLENICALLY-UNSATURED 1,3-DIKETOAMIDE FUNCTIONAL COMPOUNDS, POLYMERS THEREOF AND LATEX FORMULATIONS CONTAINING THE SAME JOHNSON S C COMM MARKETS INC (US) 2000-05-03 EP disclosed
US-5889098-A A LATEX FORMULATION COMPRISES 1,3-DIKETOAMIDE PENDANT GROUP DERIVED FROM AN ETHYLENICALLY UNSATURATED 1,3-DIKETOAMIDE FUNCTIONAL COMPOUND, A POLYFUNCTIONAL AMINE AND AN EVAPORABLE AQUEOUS CARRIER; CROSSLINKABLE; STORAGE STABILITY S. C. JOHNSON COMMERCIAL MARKETS, INC. (US) 1999-03-30 US disclosed
US-5886116-A HYDROLYTIC STABILITY S.C. JOHNSON COMMERCIAL MARKETS, INC. (US) 1999-03-23 US disclosed
US-5872297-A Ethylenically-unsaturated 1,3-diketoamide functional compounds S. C. JOHNSON COMMERCIAL MARKETS, INC. (US) 1999-02-16 US disclosed
EP-0873303-A1 ETHYLENICALLY-UNSATURED 1,3-DIKETOAMIDE FUNCTIONAL COMPOUNDS, POLYMERS THEREOF AND LATEX FORMULATIONS CONTAINING THE SAME S.C.JOHNSON & SON, INC. (US) 1998-10-28 EP disclosed
WO-1997008134-A1 ETHYLENICALLY-UNSATURATED 1,3-DIKETOAMIDE FUNCTIONAL COMPOUNDS, POLYMERS THEREOF AND LATEX FORMULATIONS CONTAINING THE SAME S.C. JOHNSON & SON, INC. (US) 1997-03-06 WO disclosed