Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820448 | 0.92 | TTR (0.56) | SNCAAPPKMT2ACYP3A4TP53 | |
| SCHEMBL10870487 | 0.91 | CYP3A4 (0.50) | SNCAAPPKMT2ACYP3A4TP53 | |
| SCHEMBL9700576 | 0.90 | CYP3A4 (0.43) | SNCAAPPKMT2ACYP3A4TP53 | |
| SCHEMBL9816881 | 0.88 | KMT2A (0.51) | SNCAAPPKMT2ACYP3A4KDM4E | |
| SCHEMBL6152948 | 0.86 | CYP3A4 (0.46) | SNCAKMT2ACYP3A4KDM4EMEN1 | |
| SCHEMBL9717273 | 0.84 | ALDH1A1 (0.48) | APPCYP3A4TP53KDM4EMAPT | |
| SCHEMBL7946937 | 0.84 | CYP3A4 (0.44) | SNCAAPPKMT2ACYP3A4KDM4E | |
| SCHEMBL9174753 | 0.83 | CYP3A4 (0.43) | KMT2ACYP3A4MEN1LMNAMAPT | |
| SCHEMBL6152601 | 0.83 | ELANE (0.49) | SNCACYP3A4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6151946 | 0.83 | ELANE (0.46) | SNCAAPPKMT2ACYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196466-B1 | POLYMERIZABLE COMPOSITION OF ALIPHATIC POLYOL (ALLYL CARBONATE) | PPG IND OHIO INC (US) | 2005-01-26 | — | — | EP | disclosed |
| US-6316570-B1 | FOR PRODUCING POLYMERIZATES HAVING CLARITY, GOOD FLEXIBILITY, ABRASION RESISTANCE WHICH ARE USED IN PREPARATION OF MOLDED ARTICLES SUCH AS LENSES | PPG INDUSTRIES OHIO, INC. | 2001-11-13 | — | — | US | disclosed |