Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870487 | 0.91 | CYP3A4 (0.50) | CYP3A4THRBKMT2AALDH1A1HSD17B10 | |
| SCHEMBL175910 | 0.87 | HTR2A (0.49) | CYP3A4THRBHTR2AKMT2AALDH1A1 | |
| SCHEMBL6152948 | 0.86 | CYP3A4 (0.46) | ELANECYP3A4THRBKMT2AALDH1A1 | |
| SCHEMBL28846119 | 0.85 | SRD5A2 (0.42) | CYP3A4THRBALDH1A1HSD17B10TSHR | |
| SCHEMBL9816881 | 0.85 | KMT2A (0.51) | CYP3A4KMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL9717273 | 0.84 | ALDH1A1 (0.48) | ELANECYP3A4THRBHTR2AALDH1A1 | |
| SCHEMBL9700576 | 0.83 | CYP3A4 (0.43) | CYP3A4THRBKMT2AALDH1A1HSD17B10 | |
| SCHEMBL6152601 | 0.83 | ELANE (0.49) | ELANECYP3A4ALDH1A1HSD17B10TSHR | |
| SCHEMBL6153149 | 0.83 | SNCA (0.51) | CYP3A4KMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL9174753 | 0.83 | CYP3A4 (0.43) | CYP3A4THRBKMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196466-B1 | POLYMERIZABLE COMPOSITION OF ALIPHATIC POLYOL (ALLYL CARBONATE) | PPG IND OHIO INC (US) | 2005-01-26 | — | — | EP | disclosed |
| US-6316570-B1 | FOR PRODUCING POLYMERIZATES HAVING CLARITY, GOOD FLEXIBILITY, ABRASION RESISTANCE WHICH ARE USED IN PREPARATION OF MOLDED ARTICLES SUCH AS LENSES | PPG INDUSTRIES OHIO, INC. | 2001-11-13 | — | — | US | disclosed |