Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660774 | 0.93 | MAPK1 (0.42) | TDP1MAPK1CYP3A4TRPA1RORC | |
| SCHEMBL166652 | 0.91 | CYP3A4 (0.54) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL29703185 | 0.91 | CYP3A4 (0.54) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL11748612 | 0.84 | MAPK1 (0.53) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL1428432 | 0.84 | TDP1 (0.56) | TDP1MAPK1CYP3A4TRPA1RORC | |
| SCHEMBL49899 | 0.82 | TDP1 (0.70) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL29365125 | 0.82 | TDP1 (0.70) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL9576009 | 0.80 | CYP3A4 (0.51) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL10533157 | 0.79 | ALDH1A1 (0.37) | TDP1MAPK1CYP3A4RORCALDH1A1 | |
| SCHEMBL9835490 | 0.79 | KDM4E (0.39) | TDP1MAPK1CYP3A4TRPA1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005511798-A | — | — | 2005-04-28 | — | — | JP | claimed |
| EP-1448732-A1 | ROOM TEMPERATURE CURABLE X-HNBR COATING | Lord Corporation (US) | 2004-08-25 | — | — | EP | claimed |
| US-20030152790-A1 | Room temperature curable functionalized HNBR coating | LORD CORPORATION | 2003-08-14 | — | — | US | claimed |
| WO-2003042309-A1 | ROOM TEMPERATURE CURABLE X-HNBR COATING | LORD CORPORATION (US) | 2003-05-22 | — | — | WO | claimed |
| EP-1512523-A1 | Tire with indicia | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003048261-A1 | ROOM TEMPERATURE CURABLE FLUOROPOLYMER COATING | LORD CORPORATION (US) | 2003-06-12 | — | — | WO | disclosed |
| WO-2003046093-A1 | ROOM TEMPERATURE CURABLE OIL RESISTANT ELASTOMER COATING | LORD CORPORATION (US) | 2003-06-05 | — | — | WO | disclosed |