Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533157 | 0.90 | ALDH1A1 (0.37) | KDM4ECYP1A2CYP2C19RORCTDP1 | |
| SCHEMBL6371515 | 0.87 | KDM4E (0.39) | KDM4ECYP1A2CYP2C19RORCTDP1 | |
| SCHEMBL9836317 | 0.86 | PPOX (0.40) | KDM4ECYP1A2CYP2C19RORCTDP1 | |
| SCHEMBL542562 | 0.82 | CYP3A4 (0.43) | KDM4ETDP1MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL9836900 | 0.81 | ALDH1A1 (0.51) | KDM4ETDP1MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL9530684 | 0.81 | LMNA (0.43) | TDP1MAPK1ALDH1A1CYP3A4HPGD | |
| SCHEMBL9529565 | 0.80 | PPOX (0.39) | TDP1MAPK1ALDH1A1HPGDPPOX | |
| SCHEMBL6153230 | 0.79 | TDP1 (0.49) | RORCTDP1MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL9530530 | 0.79 | LMNA (0.66) | KDM4ECYP1A2TDP1MAPK1ALDH1A1 | |
| SCHEMBL1428432 | 0.79 | TDP1 (0.56) | KDM4ECYP1A2CYP2C19RORCTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4818272-A | NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0241559-A1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-10-21 | — | — | EP | disclosed |