Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152667 | 0.92 | HSP90AA1 (0.42) | GAAHSP90AA1 | |
| SCHEMBL5778733 | 0.66 | HTR6 (0.31) | — | |
| SCHEMBL6153187 | 0.65 | MAPT (0.38) | GAAHSP90AA1 | |
| SCHEMBL17395292 | 0.61 | TRPV1 (0.43) | FLT3TYRO3MERTKGAS6GAA | |
| SCHEMBL1658318 | 0.57 | HSP90AA1 (0.68) | HSP90AA1 | |
| SCHEMBL4164161 | 0.57 | HSP90AA1 (0.41) | HSP90AA1 | |
| SCHEMBL8398081 | 0.56 | HSP90AA1 (0.69) | HSP90AA1 | |
| SCHEMBL6153035 | 0.56 | ALDH1A1 (0.39) | — | |
| SCHEMBL7824106 | 0.56 | KDM4E (0.45) | — | |
| SCHEMBL16824262 | 0.54 | ALDH1A1 (0.46) | TYRO3MERTKGAS6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406610-B1 | USE OF SUBSTITUTED GAMMA-LACTONE COMPOUNDS AS MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2005-01-26 | — | — | EP | claimed |
| US-6943181-B2 | Use of substituted gamma-lactone compounds as pharmaceutical preparations | GRUNENTHAL GMBH (DE) | 2005-09-13 | — | — | US | disclosed |