Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155483 | 0.96 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1ROCK2ROCK1 | |
| SCHEMBL6160095 | 0.88 | ROCK2 (0.69) | CSNK2A1ROCK2ROCK1ABCG2MGAM | |
| SCHEMBL6157313 | 0.88 | ABCG2 (0.55) | CSNK2A2CSNK2BCSNK2A1ROCK2ROCK1 | |
| SCHEMBL6153808 | 0.85 | ROCK2 (0.62) | CSNK2A1ROCK2ROCK1MGAMGAA | |
| SCHEMBL6156315 | 0.84 | ALDH1A1 (0.54) | CSNK2A2CSNK2BCSNK2A1ROCK2ROCK1 | |
| SCHEMBL6153541 | 0.84 | ROCK2 (0.56) | CSNK2A2CSNK2BCSNK2A1ROCK2ROCK1 | |
| SCHEMBL6154902 | 0.83 | ROCK2 (0.49) | CSNK2A2CSNK2BCSNK2A1ROCK2ROCK1 | |
| SCHEMBL6154247 | 0.83 | ROCK2 (0.60) | CSNK2A1ROCK2ROCK1ABCG2MGAM | |
| SCHEMBL6153975 | 0.83 | ROCK2 (0.62) | CSNK2A1ROCK2ROCK1MGAMGAA | |
| SCHEMBL6157444 | 0.82 | ROCK2 (0.67) | CSNK2A2CSNK2BCSNK2A1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | CSNK2A2 1209/4885CSNK2B 1363/4885CSNK2A1 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.