Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094047 | 0.87 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6063515 | 0.87 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL5694265 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL8297099 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL5645395 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5642882 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5644512 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6596082 | 0.79 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL27628401 | 0.78 | PTGS2 (0.97) | PTGS2PTGS1 | |
| SCHEMBL27628664 | 0.78 | PTGS2 (0.97) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499315-A1 | COMBINATION OF CYCLOOXYGENASE-2 INHIBITORS AND THALIDOMIDE FOR THE TREATMENT OF NEOPLASIA | Pharmacia Corporation (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003092691-A1 | COMBINATION OF CYCLOOXYGENASE-2 INHIBITORS AND THALIDOMIDE FOR THE TREATMENT OF NEOPLASIA | PHARMACIA COPORATION (US) | 2003-11-13 | — | — | WO | disclosed |