Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153552 | 0.85 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL6094047 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6063515 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL8297099 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8311542 | 0.80 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL6095071 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL29527405 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL214284 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8289129 | 0.77 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL6596082 | 0.76 | PTGS2 (0.61) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653967-A2 | COMBINATION OF A COX-2 INHIBITOR AND AN ALKYLATING-TYPE ANTINEOPLASTIC AGENT FOR TREATMENT OF NEOPLASIA | Pharmacia Corporation (US) | 2006-05-10 | — | — | EP | disclosed |
| EP-1653940-A1 | THERAPEUTIC COMBINATION OF A COX-2 INHIBITOR AND AN AROMATASE INHIBITOR | Pharmacia Corporation (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005018569-A2 | COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A SEROTONIN MODULATING AGENT FOR THE TREATMENT OF NEOPLASIA | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| WO-2004093856-A2 | COMBINATION OF A COX-2 INHIBITOR AND AN ALKYLATING-TYPE ANTINEOPLASTIC AGENT FOR TREATMENT OF NEOPLASIA | PHARMACIA CORPORATION (US) | 2004-11-04 | — | — | WO | disclosed |
| WO-2004093868-A1 | THERAPEUTIC COMBINATION OF A COX-2 INHIBITOR AND AN AROMATASE INHIBITOR | PHARMACIA CORPORATION (US) | 2004-11-04 | — | — | WO | disclosed |