Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.67 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | AGXT | P21549 | 2/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919554 | 0.89 | MAOB (0.59) | MAOBIDO1AGXTMRGPRX4APP | |
| SCHEMBL920589 | 0.85 | MAOB (0.67) | MAOBIDO1AGXTMRGPRX4APP | |
| SCHEMBL339853 | 0.84 | MAOB (0.69) | MAOBMRGPRX4APPABCB1HTR1A | |
| SCHEMBL14547318 | 0.84 | MAOB (0.81) | MAOBIDO1AGXTMRGPRX4ABCB1 | |
| SCHEMBL13263642 | 0.84 | MAOB (0.79) | MAOBIDO1AGXTMRGPRX4ABCB1 | |
| SCHEMBL16710547 | 0.82 | MAOB (0.71) | MAOBIDO1AGXTMRGPRX4APP | |
| SCHEMBL13462942 | 0.81 | MAOB (0.69) | MAOBIDO1AGXTMRGPRX4APP | |
| SCHEMBL791569 | 0.80 | MAOB (1.00) | MAOBMRGPRX4APPABCB1HTR1A | |
| SCHEMBL28815833 | 0.80 | MAOB (0.50) | MAOBIDO1AGXTMRGPRX4APP | |
| SCHEMBL22875 | 0.80 | MAOB (0.68) | MAOBIDO1AGXTMRGPRX4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | MAOB 3660/4885IDO1 1533/4885AGXT 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.