Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ADCYAP1R1 | P41586 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662715 | 0.90 | MAPT (0.48) | MAPTALDH1A1NPSR1L3MBTL1ACHE | |
| SCHEMBL10334906 | 0.76 | GAA (0.47) | MAPTALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL10335675 | 0.73 | IDO1 (0.51) | ALDH1A1L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL6154622 | 0.70 | SMN1; SMN2 (0.55) | MAPTALDH1A1NPSR1L3MBTL1KMT2A | |
| SCHEMBL6153416 | 0.67 | KMT2A (0.52) | MAPTALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL6156530 | 0.66 | KMT2A (0.51) | MAPTALDH1A1NPSR1L3MBTL1KMT2A | |
| SCHEMBL9292639 | 0.65 | IDO1 (0.53) | ALDH1A1NPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6154890 | 0.65 | DHODH (0.44) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6153460 | 0.64 | RRM1 (0.56) | MAPTALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL10334726 | 0.63 | IDO1 (0.54) | ALDH1A1KMT2AMEN1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | MAPT 3318/4885ALDH1A1 961/4885NPSR1 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.