Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156530 | 0.91 | KMT2A (0.51) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6153460 | 0.81 | RRM1 (0.56) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6154622 | 0.79 | SMN1; SMN2 (0.55) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6153812 | 0.76 | SMN1; SMN2 (0.49) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7516731 | 0.72 | MAPT (0.47) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6155174 | 0.71 | SLC7A5 (0.49) | GAAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6153669 | 0.71 | KMT2A (0.49) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL27954242 | 0.70 | MEN1 (0.59) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL6665515 | 0.68 | MAPT (0.52) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6155528 | 0.68 | GUSB (0.57) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | KMT2A 875/4885GAA 2365/4885ALDH1A1 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.