Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154094 | 1.00 | KDM4E (0.51) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL5889037 | 0.86 | AGTR1 (0.59) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL6150375 | 0.85 | AGTR1 (0.58) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL13754805 | 0.79 | KDM4E (0.63) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL239417 | 0.79 | KDM4E (0.63) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL239416 | 0.79 | KDM4E (0.63) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL5589232 | 0.78 | AGTR1 (0.51) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL17620785 | 0.75 | KDM4E (0.54) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL15828354 | 0.75 | KDM4E (0.54) | KDM4EAGTR1ALDH1A1TOP2ARAB9A | |
| SCHEMBL20220197 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1TOP2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542797-A2 | CATALYST SYSTEMS FOR ETHYLENE OLIGOMERISATION TO LINEAR ALPHA OLEFINS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004037415-A2 | CATALYST SYSTEMS FOR ETHYLENE OLIGOMERISATION TO LINEAR ALPHA OLEFINS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2004-05-06 | — | — | WO | disclosed |