Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154255 | 1.00 | AKT1 (0.44) | AKT1CYP1A2CYP2C9HPGDHSD17B10 | |
| SCHEMBL6154265 | 1.00 | AKT1 (0.44) | AKT1CYP1A2CYP2C9HPGDHSD17B10 | |
| SCHEMBL6881468 | 0.79 | AKT1 (0.47) | AKT1HSD17B10TBXAS1MEN1KMT2A | |
| SCHEMBL6881472 | 0.79 | AKT1 (0.47) | AKT1HSD17B10TBXAS1MEN1KMT2A | |
| SCHEMBL6879981 | 0.77 | TBXAS1 (0.41) | CYP1A2CYP2C9HPGDHSD17B10TBXAS1 | |
| SCHEMBL6879986 | 0.77 | TBXAS1 (0.41) | CYP1A2CYP2C9HPGDHSD17B10TBXAS1 | |
| SCHEMBL6879977 | 0.77 | TBXAS1 (0.41) | CYP1A2CYP2C9HPGDHSD17B10TBXAS1 | |
| SCHEMBL6154731 | 0.74 | CA12 (0.49) | HSD17B10TBXAS1 | |
| SCHEMBL6154738 | 0.74 | CA12 (0.49) | HSD17B10TBXAS1 | |
| SCHEMBL6156377 | 0.74 | CA12 (0.49) | HSD17B10TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |