Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879977 | 1.00 | TBXAS1 (0.41) | TBXAS1ALDH1A1APEX1CYP1A2CYP2C9 | |
| SCHEMBL6879981 | 1.00 | TBXAS1 (0.41) | TBXAS1ALDH1A1APEX1CYP1A2CYP2C9 | |
| SCHEMBL6154250 | 0.77 | AKT1 (0.44) | TBXAS1APEX1CYP1A2CYP2C9HPGD | |
| SCHEMBL6154265 | 0.77 | AKT1 (0.44) | TBXAS1APEX1CYP1A2CYP2C9HPGD | |
| SCHEMBL6154255 | 0.77 | AKT1 (0.44) | TBXAS1APEX1CYP1A2CYP2C9HPGD | |
| SCHEMBL6885547 | 0.76 | ALDH1A1 (0.44) | ALDH1A1APEX1CYP1A2CYP2C9HPGD | |
| SCHEMBL6154738 | 0.76 | CA12 (0.49) | TBXAS1ALDH1A1HSD17B10 | |
| SCHEMBL6156377 | 0.76 | CA12 (0.49) | TBXAS1ALDH1A1HSD17B10 | |
| SCHEMBL6154731 | 0.76 | CA12 (0.49) | TBXAS1ALDH1A1HSD17B10 | |
| SCHEMBL6879053 | 0.74 | TBXAS1 (0.49) | TBXAS1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |