Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155502 | 0.72 | MEN1 (0.43) | CASP3SENP8SENP7SENP6 | |
| SCHEMBL1241733 | 0.66 | FFAR4 (0.45) | FFAR4FFAR1NTRK1 | |
| SCHEMBL3831544 | 0.65 | HTR7 (0.39) | FFAR4FFAR1 | |
| SCHEMBL31171603 | 0.65 | HTR7 (0.39) | FFAR4FFAR1 | |
| SCHEMBL6153549 | 0.64 | CASP3 (0.38) | CASP3SENP8SENP7SENP6 | |
| SCHEMBL30165577 | 0.64 | TSHR (0.41) | FFAR4 | |
| SCHEMBL10503312 | 0.64 | TSHR (0.41) | FFAR4 | |
| SCHEMBL28802335 | 0.63 | APOBEC3G (0.59) | FFAR4FFAR1NTRK1 | |
| SCHEMBL12361207 | 0.63 | FFAR4 (0.49) | FFAR4FFAR1NTRK1 | |
| SCHEMBL2241548 | 0.63 | FFAR4 (0.45) | FFAR4FFAR1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | FFAR4 4390/4885FFAR1 4172/4885NTRK1 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.