Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793485 | 0.94 | KDM4E (0.50) | TDP1LMNAKDM4EALDH1A1HTT | |
| SCHEMBL6154976 | 0.86 | TSHR (0.49) | LMNAKDM4EALDH1A1NCOA1NCOA3 | |
| SCHEMBL8555013 | 0.79 | KDM4E (0.49) | LMNAKDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL644055 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1HTTPOLBSMN1; SMN2 | |
| SCHEMBL27009292 | 0.78 | TDP1 (0.64) | TDP1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL267613 | 0.77 | KDM4E (0.49) | TDP1LMNAKDM4EALDH1A1HTT | |
| SCHEMBL3576601 | 0.77 | LMNA (0.57) | LMNAKDM4EALDH1A1HTTNCOA1 | |
| SCHEMBL23292495 | 0.76 | MAPT (0.58) | TDP1LMNAKDM4EALDH1A1HTT | |
| SCHEMBL7797959 | 0.76 | TDP1 (0.58) | TDP1KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4849392 | 0.76 | TSHR (0.51) | LMNAKDM4EALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |