Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20959501 | 0.79 | ALDH1A1 (0.42) | ALDH1A1PKM | |
| SCHEMBL20980365 | 0.79 | ALDH1A1 (0.42) | ALDH1A1PKM | |
| SCHEMBL1005944 | 0.79 | ALDH1A1 (0.42) | ALDH1A1PKM | |
| SCHEMBL796903 | 0.79 | ALDH1A1 (0.42) | ALDH1A1PKM | |
| SCHEMBL6156594 | 0.76 | GAA (0.31) | OR51E2CRBNFKBP5GAA | |
| SCHEMBL15819417 | 0.74 | ALDH1A1 (0.37) | ALDH1A1PKM | |
| SCHEMBL15817820 | 0.74 | ALDH1A1 (0.37) | ALDH1A1PKM | |
| SCHEMBL7522167 | 0.68 | ALDH1A1 (0.37) | ALDH1A1PKM | |
| SCHEMBL5037117 | 0.68 | — | — | |
| SCHEMBL6266247 | 0.67 | MAPT (0.32) | OR51E2CRBNFKBP5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184377-B1 | Hepatobiliary magnetic resonance contrast agents | BRACCO INT BV (NL) | 2005-02-02 | — | — | EP | disclosed |
| EP-1184377-A1 | Hepatobiliary magnetic resonance contrast agents | BRACCO International B.V. (NL) | 2002-03-06 | — | — | EP | disclosed |
| WO-1995009161-A1 | HEPATOBILIARY MAGNETIC RESONANCE CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 1995-04-06 | — | — | WO | disclosed |
| US-5358704-A | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents | BRISTOL-MYERS SQUIBB (US) | 1994-10-25 | — | — | US | disclosed |