Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.52 |
| ▸ | CDK4 | P11802 | 8/20 | 0.52 |
| ▸ | CCND1 | P24385 | 8/20 | 0.52 |
| ▸ | CDK2 | P24941 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CASK | O14936 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.45 |
| ▸ | STK10 | O94804 | 1/20 | 0.45 |
| ▸ | CDK14 | O94921 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MAK | P20794 | 1/20 | 0.45 |
| ▸ | CDK11B | P21127 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154241 | 0.86 | CCR6 (0.57) | CDK2SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL6154425 | 0.86 | EHMT2 (0.50) | CDK1SMN1; SMN2JAK2JAK3GAA | |
| SCHEMBL6154337 | 0.84 | MAPT (0.52) | CDK1CDK4CCND1CDK2JAK2 | |
| SCHEMBL6154287 | 0.82 | PARP15 (0.55) | SMN1; SMN2SYKGAA | |
| SCHEMBL6154109 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AHTR4 | |
| SCHEMBL6153579 | 0.81 | KIT (0.60) | SYKMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL6153345 | 0.81 | KIT (0.60) | SYKMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL6153341 | 0.81 | KIT (0.60) | SYKMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL6154491 | 0.80 | KIT (0.47) | SMN1; SMN2SYKMEN1KMT2AGAA | |
| SCHEMBL6153322 | 0.80 | FLT3 (0.47) | CDK4CDK2SMN1; SMN2JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | CDK1 408/4885CDK4 2131/4885CCND1 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.