Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA4 | P22459 | 1/20 | 0.45 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.45 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.45 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655835 | 0.81 | KCNA4 (0.40) | KCNA4KCNA1KCNAB1DNMT3BMEN1 | |
| SCHEMBL5983432 | 0.79 | KCNA4 (0.38) | KCNA4KCNA1KCNAB1DNMT3BMEN1 | |
| SCHEMBL2422556 | 0.79 | KCNA4 (0.38) | KCNA4KCNA1KCNAB1DNMT3BMEN1 | |
| Bicarbonate SCHEMBL21906198 | 0.77 | KCNA4 (0.37) | KCNA4KCNA1KCNAB1DNMT3BMEN1 | |
| SCHEMBL3389675 | 0.76 | KCNA4 (0.36) | KCNA4KCNA1KCNAB1DNMT3BMEN1 | |
| SCHEMBL2390258 | 0.74 | HTR2C (0.32) | KCNA4KCNA1KCNAB1MEN1CYP2C19 | |
| SCHEMBL5785392 | 0.73 | KCNA4 (0.35) | KCNA4KCNA1KCNAB1DNMT3BMEN1 | |
| SCHEMBL6903379 | 0.73 | MEN1 (0.36) | KCNA4KCNA1KCNAB1DNMT3BMEN1 | |
| SCHEMBL7427186 | 0.72 | KDM1A (0.39) | MEN1CYP2C19KMT2ALMNAALDH1A1 | |
| SCHEMBL5526902 | 0.72 | KDM1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133016-B | Method for producing substituted biphenyls | BASF AG | 2010-06-02 | — | — | CN | disclosed |
| CN-101133016-A | Method for producing substituted biphenyls | BASF AG (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20050271584-A1 | Biphenyls and fluorenes as imaging agents in alzheimer's disease | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2005-12-08 | — | — | US | disclosed |
| EP-1553985-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | The Trustees of The University of Pennsylvania (US) | 2005-07-20 | — | — | EP | disclosed |
| CN-1163452-C | Process for preparing nitrobiphenylene | �����ɷ� | 2004-08-25 | — | — | CN | disclosed |
| WO-2004032975-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2004-04-22 | — | — | WO | disclosed |
| CN-1213359-A | Process for preparing nitrobiphenylene | BASF AG (DE) | 1999-04-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271584-A1 | Biphenyls and fluorenes as imaging agents in alzheimer's disease | APP, BACE2, BACE1 | KCNA4 3474/4885KCNA1 3206/4885KCNAB1 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.