Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA4 | P22459 | 1/20 | 0.36 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.36 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903379 | 0.87 | MEN1 (0.36) | KCNA4KCNA1KCNAB1MEN1CYP2C19 | |
| Bicarbonate SCHEMBL21906198 | 0.81 | KCNA4 (0.37) | KCNA4KCNA1KCNAB1MEN1CYP2C19 | |
| SCHEMBL5983432 | 0.79 | KCNA4 (0.38) | KCNA4KCNA1KCNAB1MEN1CYP2C19 | |
| SCHEMBL8655835 | 0.79 | KCNA4 (0.40) | KCNA4KCNA1KCNAB1MEN1CYP2C19 | |
| SCHEMBL9271641 | 0.77 | POLB (0.41) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL6155288 | 0.76 | KCNA4 (0.45) | KCNA4KCNA1KCNAB1MEN1CYP2C19 | |
| SCHEMBL2422556 | 0.76 | KCNA4 (0.38) | KCNA4KCNA1KCNAB1MEN1CYP2C19 | |
| SCHEMBL316145 | 0.74 | EDNRA (0.35) | CYP2C19ALDH1A1EDNRA | |
| SCHEMBL1119643 | 0.73 | THRB (0.35) | CYP2C19EDNRA | |
| SCHEMBL2508140 | 0.72 | HTR2A (0.35) | MEN1CYP2C19KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805156-B1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-12-22 | — | — | EP | disclosed |
| EP-0670855-A1 | NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012555-A1 | NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |