SCHEMBL6155306

SCHEMBL6155306

C(=NOCc1ccccc1)c1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.54
MAOA P21397 1/20 0.50
ADORA2A P29274 1/20 0.48
NR4A1 P22736 1/20 0.47
USP2 O75604 1/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 1/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 2/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
RET P07949 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6814869 1.00 G6PC1 (0.54) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL840812 0.79 NR4A1 (0.50) G6PC1MAOANR4A1USP2NPC1
SCHEMBL862025 0.79 NR4A1 (0.50) G6PC1MAOANR4A1USP2NPC1
SCHEMBL214111 0.78 G6PC1 (0.51) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL214112 0.78 G6PC1 (0.51) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL9532778 0.78 G6PC1 (0.51) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL17257435 0.77 NPC1 (0.56) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL8304519 0.77 NR4A1 (0.47) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL8304515 0.77 NR4A1 (0.47) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL8600036 0.75 KDM4E (0.45) MAOANPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3143055-A2 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP Bridgestone Corporation (JP) 2017-03-22 EP claimed
WO-2015175280-A2 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2015-11-19 WO claimed
EP-3143055-B1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORP (JP) 2019-09-04 EP disclosed
CN-102317862-B Low-temperature curable photosensitive resin composition and dry film prepared using the same LG CHEMICAL LTD 2013-08-14 CN disclosed
CN-102317862-A Low-temperature curable photosensitive resin composition and dry film prepared using the same LG CHEMICAL LTD 2012-01-11 CN disclosed
EP-1499589-A1 DERIVATIVES OF N-PHENYL(PIPERIDIN-2-YL)METHYL BENZAMIDE, THE PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2005-01-26 EP disclosed
WO-2004013100-A2 N-[PHENYL(PIPERIDIN-2-YL)METHYL]BENZAMIDE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN THERAPY SANOFI-AVENTIS (FR) 2004-02-12 WO disclosed
WO-2003089411-A1 DERIVATIVES OF N-[PHENYL(PIPERIDIN-2-YL)METHYL]BENZAMIDE, THE PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2003-10-30 WO disclosed
US-5726314-A ACETYLCHOLINESTERASE INHIBITORS AS NERVE AGENT ANTIDOTES GEORGIA TECH RESEARCH CORP. (US) 1998-03-10 US disclosed
US-5714615-A ACETYLCHOLINESTERASE ENZYME INHIBITOR, STIMULATE NICOTINIC RECEPTORS IN CENTRAL NERVOUS SYSTEM GEORGIA TECH RESEARCH CORPORATION (US) 1998-02-03 US disclosed
WO-1995021822-A1 PYRIDINIUM COMPOUNDS GEORGIA TECH RESEARCH CORPORATION (US) 1995-08-17 WO disclosed
US-5290942-A Acetylcholinesterase inhibitors GEORGIA TECH RESEARCH CORPORATION (US) 1994-03-01 US disclosed
US-5206371-A Acetylcholinesterase inhibitor GEORGIA TECH RESEARCH CORPORATION (US) 1993-04-27 US disclosed
US-5180831-A Acetylcholinesterase Inhibitors GEORGIA TECH RESEARCH CORPORATION (US) 1993-01-19 US disclosed