SCHEMBL214111

SCHEMBL214111

C(=N/O[Si](Cc1ccccc1)(Cc1ccccc1)Cc1ccccc1)\c1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.51
MAOA P21397 2/20 0.47
ADORA2A P29274 1/20 0.46
NR4A1 P22736 1/20 0.45
USP2 O75604 1/20 0.44
MEN1 O00255 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 3/20 0.41
PKM P14618 1/20 0.41
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAOB P27338 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL214112 1.00 G6PC1 (0.51) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL214074 0.84 TAAR1 (0.38) G6PC1MAOAADORA2AMEN1RAB9A
SCHEMBL214073 0.84 TAAR1 (0.38) G6PC1MAOAADORA2AMEN1RAB9A
SCHEMBL862320 0.81 NR4A1 (0.47) G6PC1MAOANR4A1USP2MEN1
SCHEMBL841340 0.81 NR4A1 (0.47) G6PC1MAOANR4A1USP2MEN1
SCHEMBL214857 0.78 PLA2G7 (0.43) G6PC1MEN1NPC1RAB9AKMT2A
SCHEMBL214856 0.78 PLA2G7 (0.43) G6PC1MEN1NPC1RAB9AKMT2A
SCHEMBL6814869 0.78 G6PC1 (0.54) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL6155306 0.78 G6PC1 (0.54) G6PC1MAOAADORA2ANR4A1USP2
SCHEMBL212865 0.76 MAOA (0.51) G6PC1MAOAADORA2ANR4A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed